A double-blind, placebo-controlled study enrolled patients who had extended histories of receiving and tolerating BOTOX injections, with prior individualized adjustment of dose. The mean BOTOX dose administered to patients in this study was 236 Units (25th to 75th percentile range of 198 Units to 300 Units). The BOTOX dose was divided among the affected muscles [see Clinical Studies (14.7)]. Dosing in initial and sequential treatment sessions should be tailored to the individual patient based on the patient’s head and neck position, localization of pain, muscle hypertrophy, patient response, and adverse event history. The initial dose for a patient without prior use of BOTOX should be at a lower dose, with subsequent dosing adjusted based on individual response.
Spread of toxin effects (this carries a Boxed warning in the Botox Prescribing Information). In some cases, the effect of botulinum toxin A may affect areas of the body away from the injection sitio and cause symptoms of a serious condition called botulism. The symptoms of botulism include: loss of strength and muscle weakness all over the body
There have been postmarketing reports of serious breathing difficulties, including respiratory failure.
Vigorous treatment of any epithelial defect should be employed. This may require protective drops, ointment, therapeutic soft contact lenses, or closure of the eye by patching or other means.
Based on animal data, onabotulinumtoxinA may harm your unborn baby. Talk to your healthcare provider about the risks of receiving this medicine during pregnancy.
OnabotulinumtoxinA is a neurotoxin that works by temporarily blocking the release of acetylcholine, a neurotransmitter responsible for triggering muscle contraction or gland secretion. Depending on the specific condition being treated, this can:
Below is a breakdown of typical unit ranges for the most common facial and neck areas using Botox Cosmetic:
The duration of post-injection catheterization for those who developed urinary retention is also shown.
Botox Cosmetic is used for aesthetic purposes to smooth wrinkles and improve the appearance of platysma bands.
Radiesse and Radiesse (+) are dermal fillers that are FDA-approved to smooth moderate to severe facial wrinkles and folds, such as nasolabial folds (the creases that extend from the corner of your nose to the corner of your mouth).1,2 Radiesse is also used for correcting volume loss in the back of the hands.3
Botox Cosmetic is injected into the specific muscles on your face that contribute to severe wrinkles or facial lines.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Este bioestimulador de colágeno Pode vir a ajudar a suavizar a celulite, pois uma vez que estimula a produçãeste conterraneo de colágeno na pele, combate a flacidez da pele e deixa bioestimulador de colágeno a pele Muito mais espessa, utilizando mais volume e Muito mais uniforme, melhorando este aspecto da pele com celulite.
These highlights do not include all the information needed to use BOTOX® safely and effectively. See full prescribing information for BOTOX. BOTOX® (onabotulinumtoxinA) for injection, for intramuscular, intradetrusor, or intradermal use Initial U.S. Approval: 1989 WARNING: DISTANT SPREAD OF TOXIN EFFECT See full prescribing information for complete boxed warning. The effects of BOTOX and all botulinum toxin products may spread from the area of injection to produce symptoms consistent with botulinum toxin effects.